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Clarksville, Missouri

The mighty Mississippi was the lifeblood of many Missouri towns for over a century. The Missouri Great River Road is a route with stories to tell and a history to preserve. Civil War History and the movement west are just two of the great American stories that the byway has to tell.

Interpretive sites are being established along this 30 mile section of the Great River Road in Missouri beginning at the southern boundary of Clarksville. Numbered signs are positioned for the visitor to make stops along the way.

Attractions and Upcoming Events

Clarksville Museum

The Clarksville Museum, operated by a volunteer board, covers the history of the town from its founding in 1817

Clarksville, MO Museums

River Heritage and Visitor Center

The Clarksville Tourist Information Center serves to showcase attractions and sights for those traveling the Great River Road. It overlooks the U. S. Lock and Dam #24, providing a close vantage point to view all river boat and barge traffic and a 'front row seat'

Clarksville, MO Visitors Centers

The Great River Road Scenic Byway

The mighty Mississippi was the lifeblood of many Missouri towns for over a century. The Missouri Great River Road is a route with stories to tell and a history to preserve. Civil War History and the movement west are just two of the great American stories that the byway has to tell.

Clarksville, MO Scenic Byways


Historic Downtown District

The commercial district in Clarksville is listed on the National Register of Historic Places

Clarksville, MO Historic Districts

Things to do near Clarksville, MO

The Cooking School at Eagles Nest

A recreational cooking school featuring 4-day classes of cuisine with chefs and instructors from around the world. Winery, in...

Center for Living History Preservation

Step back in time and see history come alive with people actually living in a historical setting. ADA ...

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Honey Shuck - Home of Champ Clark

The historic home of Champ Clark, speaker of the House of Representatives, 1911 - 1919. Restored with authentic and equivalen...